Extended GUIDE-Seq Analysis
Cleavage, repair, and translocation information
Postcede every gene edit experience with KBioBox's extended GUIDE-Seq analysis to gain vital information to the exact results of the edit.
Identify actual cleavage sites, correct and incorrect repairs, observed and potential translocations and the changes to peptide/protein sequences.
Three Critical Checks
for any gene edit
Where did the nuclease cleave in intended and unintended targets, and how frequently. Ensure the accuracy of the nuclease and guide.
Did the DNA/RNA repair as intended or did undesired indels,SNPs, or translocations occur
Discover observed translocations, and the potential for other translocations and the resulting changes to peptide sequence.
Better GUIDE-Seq Analysis
Observed Off Targets
Identify, annotation and visualize all sites affected by the gene edit.
Gain information on observed cleavage sites and their frequency.
Correct and incorrect repair occurrences and frequency
Flag observed and potential translocations, and the effects to peptide sequences.