Extended GUIDE-Seq Analysis
Cleavage, repair, and translocation information
Starting at $5000 per run
KBioBox Extended GUIDE-Seq analysis significantly enhances the standard procedure and identifies actual cleavage sites, correct and incorrect repairs, observed and potential translocations and the changes to peptide/protien sequences.
Better GUIDE-Seq Analysis
Three Critical Checks
for any gene edit
Cleavages
![Generic placeholder image](https://www.kbiobox.com/assets/checkedit_cleavages-165bd7f92c6beca41572c0e19727adbb51dee7a0ab329ef4af18ae43e693c805.png)
Where did the nuclease cleave in intended and unintended targets, and how frequently. Ensure the accuracy of the nuclease and guide.
Repairs
![Generic placeholder image](https://www.kbiobox.com/assets/checkedit_repairs-8b567613c7d113c12c63bf53e8a9e371fc50837932a92ab21cca37a9cc323dde.png)
Did the DNA/RNA repair as intended or did undesired indels,SNPs, or translocations occur
Translocations
![Generic placeholder image](https://www.kbiobox.com/assets/checkedit_trans-12823b61483c6ed4ce75ab0cdceed21f773862c3c0da8f737c120f20e3be91d2.png)
Discover observed translocations, and the potential for other translocations and the resulting changes to peptide sequence.
Postcede every gene edit experience with KBioBox's extended GUIDE-Seq analysis to gain vital information to the exact results of the edit.
Identify actual cleavage sites, correct and incorrect repairs, observed and potential translocations and the changes to peptide/protein sequences.
Report Highlights
![](https://www.kbiobox.com/assets/fast-search-icon-c84e1e35ba75e98d29956d3f5379141775b0f11e35a86d17a43a64a61c45406c.png)
Observed Off Targets
Identify, annotation and visualize all sites affected by the gene edit.
![](https://www.kbiobox.com/assets/annotate-icon-251853dcbe75c74c5a3950c5730c3b01fb43ec72ab965d34933343a6786b3ab7.png)
Cleavages
Gain information on observed cleavage sites and their frequency.
![](https://www.kbiobox.com/assets/biotech-icon-04ee6047779a6c7258f212e1ff91d8bc17cd9563560fc4600cefb744f5671f39.png)
Repairs
Correct and incorrect repair occurrences and frequency
![](https://www.kbiobox.com/assets/custom-app-icon-3adbdb18ae13e080072c2633b3300ec30e5e4cc565e919c86c8b03f50379f025.png)
Translocations
Flag observed and potential translocations, and the effects to peptide sequences.